出生年月：1989-04

民族：漢

職稱(chēng)：講師

學(xué)科專(zhuān)業(yè)：藥物化學(xué)

研究方向：天然藥物化學(xué)/真菌化學(xué)

電子郵箱：2021068@mail.scuec.edu.cn

一、教育和工作經(jīng)歷

2023.04-至今：中南民族大學(xué)，藥學(xué)院，講師

2021.07-2024.07：中南民族大學(xué)，藥學(xué)院，預(yù)備師資

2018.09-2021.07：中國(guó)科學(xué)院昆明植物研究所，理學(xué)博士

2015.09-2018.07：中國(guó)科學(xué)院昆明植物研究所，理學(xué)碩士

2011.09-2015.07：云南農(nóng)業(yè)大學(xué)，農(nóng)學(xué)學(xué)士

二、研究方向：

1.藥用植物藥效物質(zhì)基礎(chǔ)及生物功能研究

2.真菌天然產(chǎn)物的結(jié)構(gòu)及生物功能研究

三、主持的科研項(xiàng)目：

(1) 國(guó)家自然科學(xué)基金青年基金項(xiàng)目, 82204239，2023-01至2025-12，主持

(2) 湖北省自然科學(xué)基金青年基金, 2022CFB920，2022-12至2024-06，主持

(3) 中央高校基本科研業(yè)務(wù)費(fèi)專(zhuān)項(xiàng)資金自科青年項(xiàng)目, CZQ23047, 2023-04至2026-04，主持

四、代表性研究成果

(1) Shi Baobao, Lu Jingsong, Wu Jing, Bao Meifen, Cai, Xianghai , Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia. Organic Chemistry Frontiers, 2021, 8(11): 2601-2607.

(2) Shi Baobao, Kongkiatpaiboon Sumet, Chen Gao, Schinnerl Johann, Cai* Xianghai, Nematocidal alkaloids from the roots of Stemona mairei (H.Lév.)K.Krause and identification of their pharmacophoric moiety. Bioorganic Chemistry, 2023, 130: 106239.

(3) Ai Honglian¹, Shi Baobao¹, Li Wei¹, He Juan, Li Zhenghui, Feng Tao*, Liu Jikai*, Bipolarithizole A, an antifungal phenylthiazole-Sativene merosesquiterpenoid from potato endophytic fungus Bipolaris eleusines. Organic Chemistry Frontiers, 2022, 9(7): 1814-1819.

(4) Shi BaoBao¹, Tian Chun¹, Lv Xiao, Schinnerl Johann, Ye Ke, Guo Hui, Xu Fan, He Yu, Ai, HongLian* ; Liu JiKai*, Boerelasins A-D, Four Unprecedented Cytochalasins from the Endophytic Fungus Boeremia Exigua. Journal of Organic Chemistry, 2023, 88: 13926-13933

(5) Shi Baobao¹, Ai Honglian¹, Duan Kaiting, Feng Tao*, Liu Jikai*, Ophiorrhines F and G, key biogenetic intermediates of ophiorrhine Alkaloids from Ophiorrhiza japonica and their immunosuppressant activities. Journal of Natural Products, 2022, 85(2): 453-457.

(6) Shi BaoBao¹, Xu Fan¹, Zhang GuangRu, He Yu, Liu Qing, Feng MengLin, Li ZhengHui*, Liu JiKai*. Glucoconjugated monoterpene indole alkaloids with xanthine oxidase inhibitory activity from Ophiorrhiza japonica. Phytochemistry, 2024, 224, 114169.

(7) Fan YinZhong, Tian Chun, Tong ShunYao, Liu Qing, Xu Fan, Shi BaoBao*, Ai HongLian*, Liu JiKai*, Chromones from the endophytic fungus Bipolaris eleusines. Phytochemistry, 2024, 221: 114046.

(8) Fan YinZhong, Shi BaoBao*. Endophytic fungi from the four staple crops and their secondary metabolites. International Journal of Molecular Sciences, 2024, 25(11): 6057

(9) Ai Honglian¹, Lv Xiao¹, Ye Ke, Wang Mengxi, Huang Rong, Shi, Baobao*, Li, Zhenghui*. Four new highly oxygenated eremophilane sesquiterpenes from an endophytic fungus Boeremia exigua Isolated from Fritillaria hupehensis. Journal of Fungi, 2022, 8:492.

(10) Shi Baobao, Chen, Jing, Bao, Meifen, Zeng Ying*, Cai, Xianghai*. Alkaloids isolated from Tabernaemontana bufalina display xanthine oxidase inhibitory activity. Phytochemistry, 2019, 166: 112060.

(11) Zhang Xian, Fan Yinzhong, Ye Ke, Pan Xiaoyan, Ma Xujun, Ai Honglian*, Shi Baobao*, Liu Jikai*. Six unprecedented cytochalasin derivatives from the potato endophytic fungus Xylaria curta E10 and their cytotoxicity. Pharmaceuticals, 2023, 16: 193

(12) Shi Baobao¹, Zhang Guangru¹, Li Zhenghui *, Liu Jikai*. Three new oxygenated yohimbane-type alkaloids from Ophiorrhiza japonica. Fitoterapia, 2023, 166: 105442.

(13) Shi Baobao, Wang Fang, Chen Gao, Schinnerl Johann*, Zeng Ying*, Cai*, Xianghai. Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities. Tetrahedron, 2021, 79: 131783.

(14) Tian Chun, Xu Fan, He Yu, Ai Hong-Lian, Shi BaoBao*, Liu JiKai,* Isolation, absolute configuration and immunosuppressant activities of pyrrole and furanone derivatives from the edible mushroom Grifola frondose. Phytochemistry Letters, 2024, 61, 242-243

(15) Xu Fan¹, Pan Xiaoyan¹, Cai Baixiang, Fan Yinzhong, Shi Baobao*, Liu Jikai*, Currephila A, a new chromanol derivative from the endophytic fungus Curreya pityophila. Records of Natural Products, 2024, 18, 285-289.

五、近年授權(quán)專(zhuān)利：

（2）石寶寶, 劉吉開(kāi), 艾洪蓮, 馮濤, 李正輝。一種來(lái)源于日本蛇根草的新型異胡豆苷類(lèi)衍生物及其制備方法和應(yīng)用，ZL202210074390.1

（3）劉吉開(kāi), 石寶寶, 黃蓉, 王獻(xiàn), 陳乾, 董智慧, 沈慧慧, 伍興。一種細(xì)葉萼距花精致組分和單體化合物的制備方法及其在化妝品中的應(yīng)用, ZL202310428961.1