肖新才
肖新才 教授 湖北省新世紀高層次人才工程第三層次人選,主要從事新型給藥系統研制和生物醫用材料的研究。組建了民族藥物的新型給藥系統及其示蹤評價研究團隊。針對民族醫藥具有多成分、弱效應、協調整合作用特點,本團隊研究內容包括多組分藥物的化學成分分析、藥效分析、給藥系統設計(包括納米給藥,經皮給藥,靶向給藥)、劑型制備、工業化設備和工藝研究、以及臨床前研究和臨床研究等一系列研究。目的是為了讓產于民族地區的和在民族地區廣泛應用的天然藥物的劑型升級和價值提升,因而對民族醫藥賦予時代感。
學習經歷
1992.09---1996.07 在武漢化工學院就讀并獲化工過程機械工學學士學位
1996.09---1999.06 在武漢化工學院就讀獲化工過程機械工學碩士學位
2000.09---2003.06 在四川大學就讀獲化工過程機械工學博士研究生
工作經歷
1999.07-2000.08 武漢化工學院從事教學和科研工作,講師;
2003.09-2006.02: 武漢大學化學學院從事博士后工作;
2006.02- 中南民族大學生命科學學院、藥學院從事教學和科研工作,副教授、教授
重要學術組織任職情況
國際期刊Journal of Applied Polymer Science評審專家,2006年8月起
湖北省創新基金項目評審專家,2006年5月起
承擔的重要項目:
1.微重力下梯度型快速環境響應凝膠的構建、結構模擬及釋藥示蹤,國家自然科學基金項目(21978329),2020.1—2023.12, 主持;
2. 分載兩類藥的耦合式環境響應型靶向給藥系統的研究, 國家自然科學基金項目(21276287),2013.1—2016.12, 主持;
3.環境感應微泵元件的研制及其控釋放傳質特性, 國家自然科學基金項目(20976202),2010.1—2012.12, 主持;
4.環T型結構溫度敏感凝膠微球研制及其給藥特性研究,湖北省自然科學基金(2009CDB161),2010.1—2011.12, 主持。
代表作:
1. Liu Meng, Zhao Dan, Lv Hui, Liang Yun-Jing, Yang Yan-Nan, Hong Zong-Guo, Liu Jing-Xue, Dai Kang ?, Xiao Xin-Cai ?. Controllable fabrication and oil-water separation properties of polyethylene terephthaloyl- ethylenediamine-IPN-poly(N-Isopropylacrylamide) microcapsules, Polymers 2023, 15(1): 53.
2. Tan Hong-Fei, Zhao Dan, Liu Ming-Xing, Hong Zong-Guo, Liu Jing-Xue, Dai Kang ?, Xiao Xin-Cai ?. Docking design of the different microcapsules in aqueous solution and its quantitative on-off study, Polymers 2023, 15(5): 1131.
3. Xiong Xiao-Cui, Zhao Dan, Dai Kang, Xiao, Xin-Cai?. Coaxial ring-layered poly(N-isopropylacrylamide) gel columns of improved thermoresponses. Materials Chemistry and Physics 2019, 253(10): 123421.
4. Dan Zhao, Ma Wen-Ting, Xiao Xin-Cai ?. Recognition of sweat latent fingerprints with green-emitting carbon dots. Nanomaterials 2018, 8, 612(1-10) .
5. Zhang Rui-Lian, Guan Ya-Lan, Xiao Mi, Xiao Xin-Cai ?. Mobile gates driven by intermolecular hydrogen bonding. ChemistrySelect 2017, 2, 279 –282.
6. Du Huan-Huan,Xiao Xin-Cai ?.Fabrication of rapidly-responsive switches based on the coupling effect of polyacrylamide and poly(acrylic acid) without IPN structures.RSC Advances 2015,5:88021-88026.
7. Li Ying, Xiao Xin-Cai ?. Laterally sandwich-typed hydrogel columns with liner poly(N- isopropylacrylamide) layer: Preparation, swelling/deswelling kineticsanddrug delivery characteristics. Journal of Wuhan University of Technology-Materials Science Edition 2012, 27: 115-119.
8. Lu Cheng, Xiao Xin-Cai ?. Poly(N-isopropylacrylamide)-based vertically sandwich-typed hydrogel with fast temperature-response speed and its controlled- release characteristics. Journal of Wuhan University of Technology- Materials Science Edition 2012, 27: 280-284.
9. Xiao Xin-Cai?. A novel structure having linear poly(N-isopropylacrylamide) chains with rapid response to temperature changes. Advanced Materials Research 2012, 396-398: 205-208.
10. Wang Zhen-Huan, Xiao Xin-Cai ?. Preparation of core-shell microspheres by changing reaction solvent. Advanced Materials Research 2013, 634-638:2242-2245.
11. Xiao Xin-Cai,Hong Zong-Guo?. Firstborn microcrystallization method to prepare nanocapsules containing artesunate. International Journal of Nanomedicine 2010, 5: 483–486.
12. Xiao Xin-Cai ?. Effect of the initiator on thermosensitive rate of poly(N-isopropylacrylamide) hydrogels. eXPRESS Polymer Letter 2007,1: 232–235.
13. Xiao Xin-Cai ?. Surface-ionized thermosensitive poly(N-isopropylacrylamide) hydrogels with faster response. e-Polymers 2007, 091
14. Xiao Xin-Cai, Zhuo Ren-Xi ?, Xu Jian, Chen Li-Gui. Effects of reaction temperature and reaction time on positive thermosensitivity of microspheres with poly(acrylamide)/ poly(acrylic acid) IPN shells. European Polymer Journal 2006, 42: 473-478.
15. Xiao Xin-Cai, Chu Liang-Yin, Chen Wen-Mei, Wang Shu, Xie Rui. Preparation of submicron-sized monodispersed thermoresponsive core-shell hydrogel microspheres. Langmuir 2004, 20: 5247-5253.
16. Xiao Xin-Cai, Chu Liang-Yin, Chen Wen-Mei, Wang Shu, Li Yan. Positively thermo-sensitive monodisperse core-shell microspheres. Advanced Functional Materials 2003, 13: 847-852.
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