出生年月：1990-01

民    族：漢

職    稱：副教授

學科專業：真菌天然產物化學與合成生物學

郵    箱：xinyangli@scuec.edu.cn

教育經歷

2015.09-2019.06：浙江大學，醫學博士

2012.09-2015.06：南京中醫藥大學，醫學碩士

2008.09-2012.06：陜西中醫藥大學，醫學學士

工作經歷

2023.07至今：中南民族大學藥學院，副教授

2019.09-2022.03，東京大學，博士后，合作導師：Ikuro Abe教授

主要研究方向

1.   真菌天然產物生物合成途徑解析

2.   真菌天然產物生物合成酶學機制研究

3.   基于基因組挖掘手段的天然產物發現及其生物合成研究

科研項目

國家自然科學基金青年基金項目（22307148），2024.01-2026.12，主持

代表性研究成果

1.    Xinyang Li, Jinzhong Xu*, Pinmei Wang, Wanjing Ding. Novel Indole Diketopiperazine Stereoisomers from a Marine-Derived Fungus Aspergillus sp. Mycology. 2023, 14, 1-10.

2.    Xinyang Li^?, He-Ping Chen^?, Lin Zhou^?, Jing Fan, Takayoshi Awakawa, Takahiro Mori, Richiro Ushimaru*, Ikuro Abe*, Ji-Kai Liu*. Cordycicadins A-D, Antifeedant Polyketides from the Entomopathogenic Fungus Cordyceps cicadae JXCH1. Org. Lett. 2022, 24, 8627-8632.

3.    Qing-Yuan Wang^?, He-Ping Chen^?, Kai-Yue Wu, Xinyang Li*, Ji-Kai Liu*. Antibacterial and β-Site amyloid precursor protein cleaving enzyme 1 inhibitory polyketides from the fungus Aspergillus chevalieri. Front. Microbiol. 2022, 13, 1051281.

4.    Lin Zhou^?, He-Ping Chen^?, Xinyang Li*, Ji-Kai Liu*. Ganoaustralins A and B, Unusual Aromatic Triterpenes from the Mushroom Ganoderma australe. Pharmaceuticals. 2022, 15, 1520.

5.    Xinyang Li^?, Takayoshi Awakawa^?, Takahiro Mori, Meiqi Ling, Bin Wu, Ikuro Abe*. Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. J. Am. Chem. Soc. 2021, 143, 21425-21432.

6.    Xinyang Li, Jian-ming Lv, Dan Hu, Ikuro Abe*. Biosynthesis of Alkyne-containing Natural Products. RSC Chem. Biol. 2021, 2, 166-180.

7.    Suoyu Cen, Jia Jia, Yichao Ge, Yihan Ma, Xinyang Li, Jihua Wei, Yuefan Bai, Xiaodan Wu, Jianfeng Song, Hongkai Bi, Bin Wu*. A New Antibacterial 3,5-dimethylorsellinic Acid-based Meroterpene from the Marine Fungus Aspergillus sp. CSYZ-1. Fitoterapia, 2021, 152, 104908.

8.    Jinyan Jiang, Xinyang Li, Takahiro Mori, Takayoshi Awakawa*, Ikuro Abe*. Novel Cyclohexyl Meroterpenes Produced by Combinatorial Biosynthesis. Chem. Pharm. Bull., 2021, 69, 444-446.

9.    Xinyang Li, Wanjing Ding, Pinmei Wang, Jinzhong Xu*. Two Novel Aspochalasins from the Gut Fungus Aspergillus sp. Z4. Mar. Drugs, 2018, 16, 343.

10. Xinyang Li, Zhanhai Zhao, Wanjing Ding, Bin Ye, Pinmei Wang, Jinzhong Xu*. Aspochalazine A, a Novel Polycyclic Aspochalasin from the Fungus Aspergillus sp. Z4. Tetrahedron Lett, 2017, 58, 2405-2408.

(^?Co-first author; *Corresponding author)