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楊小龍

發布時間:2019-12-23 瀏覽次數:

 

 

出生年月19839

民族:漢族

職稱:二級教授/博士生導師

學科專業:藥物化學

研究方向:天然藥物化學/天然藥物生物合成與合成生物學/中藥資源化學及質量控制

電子郵箱yxl19830915@163.com

 

  • 教育及工作經歷

    2019.3-至今:  中南民族大學藥學院,教授/博士生導師

    2016.2-2019.2:重慶大學藥學院,入選重慶大學百人計劃學者,研究員/博士生導師

    2014.5-2015.5:德國漢諾威大學生物分子藥物研究中心,博士后,合作導師: Russell J. Cox

    2012.4-2014.4:日本東京大學藥學院,JSPS外國特別研究員,合作導師: Ikuro Abe

    2009.9-2012.4:河北大學藥學院,副教授/碩士生導師

    2004.9-2009.7:中科院昆明植物研究所,博士(碩博連讀),導師:劉吉開教授

    2000.9-2004.7:西北農林科技大學,理學學士

     

  • 主要榮譽和獲獎

    2022年:入選國家“萬人計劃”青年拔尖人才

    2020年:入選國家民委中青年英才

    2016年:入選重慶大學“百人計劃”學者

    2012年:獲得日本振興學會(JSPS)外國特別研究員

     

  • 學術和社會兼職

    [1] 國際SCI期刊Journal of FungiIF=5.816),客座編輯(2022.4-2022.12

    [2] 國際期刊Drug Discoveries & Therapeutics,編委(2018-至今)

    [3] 中國民族醫藥學會健康產業分會,常務理事(2022.11-至今)

    [4] 中國植物學會藥用植物及植物藥專業委員會委員(2023.12-至今)

    [5] 中國菌物學會菌物化學專業委員會,委員(2018-至今)

    [6] 湖北省生物工程學會,理事(2021-至今)

    [7] 湖北省植物學會/武漢市植物學會,理事(2021-至今)

    [8] 青海省藏藥研究重點實驗室第二屆學術委員會,委員(2022-至今)

    [9] 青海省高原天然產物工程技術研究中心,技術專家(2021-至今)

    [10] 中國科學院藏藥研究重點實驗室,客座研究員(2018 -至今)

    [11] 吉林大學,研究生校外合作導師(2019-至今)

    [12] 廣西科學院,客座研究員(2020 -至今)

    [13] 新疆農業大學,碩士生導師(2021-至今)

    [14] 楊凌未來中科環保科技有限公司,技術總監(2021-至今)

    [15] 新疆阿拉山口市金陸工程項目管理有限公司科技創新板塊,專家顧問(2022-至今)

    [16] 廣西海洋天然產物與組合生物合成化學重點實驗室學術委員會,委員(2018 -2020

    [17] 中國科學院西北高原生物研究所,客座研究員(2018 -2021

    [18] 重慶市紫杉烷類藥物工程技術研究中心專家委員會副主任 2016.10-2019.3

    [19] 曾擔任重慶大學藥學院黨委委員和教工黨支部書記(2016.12-2019.3

    [20] 曾擔任重慶大學藥學院藥物分析、藥物設計與天然藥物學系副主任(2018.10-2019.3

    [21] 受邀擔任Advanced Science, J. Am. Chem. Soc., Small, J. Org. Chem., Org. Biomol. Chem., J. Nat. Prod., Front. Microbiol., Int. J. Mol. Sci., J. Pharm. Pharmaco., Metabolites, J. Cell Mol. Med., Phytochemistry等多個SCI期刊審稿人。

     

     

  • 教學工作

    累計承擔多門課程教學工作,本科生課程包括:《有機波譜解析》、《天然藥物化學》、《天然藥物化學實驗》、《藥理學實驗》、《生理解剖學實驗》和《藥劑學實驗》,研究生課程包括:《高等天然藥物化學》和《高等有機化學》;發表國家級核心教研論文2篇;作為校級第一個跨學科科普教學實踐團隊骨干參與制作了2部科普課程《科普·神奇世界的解密者》和《帶你認識中醫藥》,上線學習強國平臺;指導大學生創新訓練項目/學科競賽20余項,獲國家級/省部級獎項7項。

     

  • 承擔科研或人才項目

    [1] 國家“萬人計劃”青年拔尖人才計劃190萬,2023.1-2025.12,主持,在研。

    [2] 國家重點研發計劃中醫藥現代化研究重點專項子課題白術、菊花和百合產地溯源檢測數據集構建2020YFC1712703),266.73萬,2020.10-2022.9,主持,結題。

    [3] 國家重點研發計劃“食品營養與安全關鍵技術研發”專項子課題:風險因子智能挖掘與多維表征(2023YFF1104001),95萬元,2023. 12 -2027.12,主持,在研。

    [4] 國家自然科學基金面上項目:基于MDM2/mTOR雙靶點的植物內生真菌中新穎結構抗三陰乳腺癌活性分子發現及其作用機制研究(82473805)48萬元,2025.01-2028.12,主持,在研。

    [5] 國家自然科學基金面上項目基因組挖掘驅動的翹孢霉屬真菌中隱形聚酮-非核糖體肽類化合物的發現及其生物合成研究(82073714)55萬元,2021.01-2024.12,主持,在研。

    [6] 國家自然科學基金面上項目表觀遺傳修飾策略驅動的11株植物內生真菌中新型抗耐藥菌活性分子合成潛能的挖掘(81872755) 57萬元,2019.01-2022.12,主持,結題。

    [7] 國家自然科學青年基金:擬盤多毛孢內生真菌中抗腫瘤活性先導化合物的發現及活性評價 (21202033) 25萬元,2013.01-2015.12,主持,結題。

    [8] 國家民委中青年英才培養計劃項目:兩株藥用植物內生真菌中新型抗腫瘤藥物先導結構的發現及其作用機制研究,10萬元,2021.01-2022.12,主持,結題。

    [9] 中央高校基本科研業務費專項資金重點培育項目:六種藥用植物內生真菌中新型抗耐藥性細菌藥物先導化合物的發現(CZP20007), 40萬,2020.1-2022.12,主持,結題。

    [10] 河北省自然科學基金:特殊生境真菌中結構新奇化學成分的發現及抗真菌活性研究 (C2012201047) 3萬元,2012.01-2015.01,主持,結題。

    [11] 中國科學院藏藥研究重點實驗室開放課題:青藏高原特境真菌資源庫構建及藥用活性分子發現 (2017-ZJ-Y11)5萬元,2018.11-2019.12,主持,結題。

    [12] 重慶大學百人計劃學者引進啟動基金:特殊生境真菌資源庫的構建及新穎結構藥用活性物質的挖掘 (0236011104401) 100萬元,2016-2019,主持,結題。

    [13] 橫向課題:抗菌消炎類物質的發現及其在新型煙草中的應用研究, 79萬元,2019.9-2021.2,主持,結題。

    [14] 橫向課題:病害丹參應激化學成分及其抗病活性研究,25萬元,2018.12-2019.12,主持,結題。

    [15] 橫向課題:一株假單胞細菌代謝產物的活性檢測及分離鑒定, 15萬元,2020.3-2021.1,主持,結題。

    [16] 橫向課題:產紫衫醇微生物的發現及產業化研究(02360126051001)100萬元,2016.05-2017.12,主持,結題。

    [17] 橫向課題:浙產鐵皮石斛活性成分提取和分離研究(HZY23027)30萬元,2023.3-2023.12,主持,結題。

     

     

  • 著作

    [1] 《民族植物資源化學與生物活性研究》20222月,化學工業出版社,第一主編

    [2]《天然產物結構解析》201711月,科學出版社,編委

    [3] 《科普:神奇世界的解密者》數字課程,20234月,電子工業出版社,副主編

    [4] 《武陵山區藥用及食用植物資源-湖北冊》,202310月,化學工業出版社,副主編

     

  • 論文發表

    迄今,在Angew. Chem. Int. Ed., Chem. Sci., Nat. Prod. Rep., Org. Lett., Cell Death Dis., J. Nutri. Biochem.等本領域權威期刊上發表學術論文120余篇,其中SCI收錄論文101篇。

  • 5年代表性SCI論文

    [1] Qing-Pei Liu#, Shuai-Biao Gao#, Jin Fang#, Yi-Fu Gong, Yi-Ling Zheng, Yao Xu, Dan Zhang, Jia-Yuan Wei, Liang-Xiu Liao, Ming Yao, Wen-Jing Wang, Xiao-Le Han, Fu-Sheng Chen, Istva?n Molna?r*, Xiao-Long Yang*. Novel fungal diphenyl ether biosynthetic gene clusters encode a promiscuous oxidase for elevated antibacterial activities. Chemical Science, 2024, 15: 14248.

    [2] Ming Yao, Wei Yang, Jing Li, Cheng-Yun Huang, Jin Fang, Su-Lu Qin, Shu-Zhi Liu, Xiao-Long Yang*. Total synthesis and stereochemical assignment of talaroconvolutin A and talarofuranone: gram-scale synthesis of ferroptosis inducer talaroconvolutin A. Chinese Journal of Chemistry, 2024, 42, 1509-1514.

    [3] Ting Wu#, Wen-Jing Wang#, Zhou-Yuan Li, Yi-Tian Liu, Tian-Ping Yu, Shuang-Ge Li, Hong-Zhi Du, Chun Gui, Da-Hui Liu*, Xiao-Long Yang*. Anti-inflammatory discovery of sesquiterpenoids and a jasmonic acid derivative from Artemisia stolonifera. Phytochemistry, 2024, 223:114120.

    [4] Liang-Xiu Liao, Jun-Guo Huang, Qing-Pei Liu, Ming Yao, Wen-Jing Wang*, Xiao-Long Yang*. Two new quinazoline alkaloids produced by Aspergillus versicolor and their antimicrobial activities. Journal of Asian Natural Products Research, 2024, 26: 320-327.

    [5] Xu Chen, Zheng-Ping Che, Jia-Jia Wu, Cheng Zeng, Xiao-long Yang*, Lin Zhang*, Zheng-Hong Lin*. Sterigmatocystin induces autophagic and apoptotic cell death of liver cancer cells via downregulation of XIAP. Heliyon, 2024, 10: e29567.

    [6] Shu-Zhi Liu#, Wen-Jing Wang#, Qing-Pei Liu, Ming Yao, Liang-Xiu Liao, Shuai-Biao Gao, Yi Yu, Xiao-Long Yang*. Emerindanols A and B: two bipolyhydroindenol sesterterpenes with unprecedented 5/6-6/5 coupled ring system discovered by genome mining. Organic Letters, 2024, 26:4475-4479

    [7] Xin-Tian Wang, Heng-Ye Chen, Yao Fan, Wei Lan, Juan He, Hai-Yan Fu*, Xiao-Long Yang*. Atractylodin targeted visual fluorescence sensor based on N-acetyl-L-cysteine capped CdTe QDs for the rapid identification of the geographical origin of Atractylodis Rhizome. Microchemical Journal, 2024, 201: 110508.

    [8] Qing-Pei Liu, Dan Zhang, Shuai-Biao Gao, Xian-Hua Cai, Ming Yao, Yao Xu, Yi-Fu Gong, Ke Zheng, Yi-Gui Mao, Li-Yan Yang, Deng-Feng Yang, Istva?n Molna?r*, Xiao-Long Yang*. Didepside formation by the nonreducing polyketide synthase Preu6 of Preussia isomera requires the interaction of the starter acyl transferase and the thioesterase domains. Angewandte Chemie International Edition, 2023, 135: e202214379.

    [9] Yong Xia#*, Long-Quan Xiang#, Ming Yao, Zhi-Ying Ai, Wei Yang, Jian-Hua Guo, Shu-Hao Fan, Ning Liu, Xiao-Long Yang*. Proteomics, transcriptomics, and phosphoproteomics reveal the mechanism of talaroconvolutin-A suppressing bladder cancer via blocking cell cycle and triggering ferroptosis. Molecular & Cellular Proreomics, 2023, 22: 100672.

    [10] Liang-Xiu Liao, Ze-Diao Huang, Fu-Ting Wei, Wen-Jing Wang*, Xiao-Long Yang*. New chromone analog and pyrrole alkaloid produced by Penicillium sclerotiorum and their antibacterial activity. Journal of Asian Natural Products Research, 2023, 25:225-230.

    [11] Ming Yao, Xiu-Yun Bai, Fa-Min Wen, Kai-Hui Liu, Jian Yang, Heng-Ye Chen*, Xiao-Long Yang*. Accurate origin identification of Chinese white Chrysanthemi Flos by analysis of C, N, O, H stable isotope ratios and mineral elements combined with chemometrics. Journal of Food Composition and Analysis, 2023, 124:105703

    [12] Su-Lu Qin, Jia-Xin Ding, Cheng-Yun Huang, Jing Li, Ming Yao, Qing-Pei Liu, Wen-Jing Wang*, Xiao-Long Yang*. Secondary metabolites from Pseudallescheria boydii and their anti-melanoma activity. Tetrahedron, 2023, 147: 133663.

    [13] Jing Li*, Sheng-Ping Jiang, Cheng-Yun Huang, Bai-Hui Lu, Xiao-Long Yang*. Identification and validation of genes associated with aging- related cardiovascular disease. The FASEB Journal, 2023, 38: e23370.

    [14] Jing Li#, Ying-Jiang Zhang#, Xin Zeng, Ya-Hong Cheng, Liu Tang, Hong Ding*, Xiao-Long Yang*. Lycopene ameliorates insulin resistance and increases muscle capillary density in aging via activation of SIRT1. Journal of Nutritional Biochemistry, 2022, 99:108862.

    [15] Qing-Pei Liu#,*, Dan Zhang#, Yao Xu, Shuai-Biao Gao, Yi-Fu Gong, Xian-Hua Cai, Ming Yao*, Xiao-Long Yang*. Cloning and functional characterization of the polyketide synthases based on genome mining of Preussia isomera XL-1326. Frontiers in Microbiology, 2022, 13: 819086

    [16] Peng-Jie Xian#, Shu-Zhi Liu#, Wen-Jing Wang, Sheng-Xiang Yang, Zhang Feng*, Xiao-Long Yang*. Undescribed specialised metabolites from the endophytic fungus Emericella sp. XL029 and their antimicrobial activities. Phytochemistry, 2022, 202: 113303.

    [17] Wen-Jing Wang#, Liang-Xiu Liao#, Ze-Diao Huang, Fu-Ting Wei, Xiao-Long Yang*. Thiazolo[5,4-b]pyridine alkaloid and seven ar-bisabol sesquiterpenes produced by the endophytic fungus Penicillium janthinellum. ACS Omega, 2022, 7: 35280-35287.

    [18] Jing Li, Xin Zeng, Xiao-Long Yang*, Hong Ding*. Lycopene ameliorates skin aging by regulation of the insulin resistance pathway and activation of SIRT1, Food & Function, 2022, 13:11307.

    [19] Li Wang, Yi-Gui Mao, Xiang Zeng, Na Liu, Chao-Fei NiuXin-Xin Li, Bi-Ji Ma*, Lan-Ping Guo*, Xiao-Long Yang*. Structure and bioactivities of a novel polysaccharide extracted from Dendrobium huoshanense by subcritical water. Frontiers in Nutrition, 2022, 9:877871.

    [20] Xiao-Le Han*,#, Fan Yu#, Jia-Wen Lei, Jia-Hua Zhu, Hai-Yan Fu, Jun-Cheng Hu, Xiao-Long Yang*. Pb2+ responsive Cu-In-Zn-S quantum dots with low cytotoxicity. Frontiers in Chemistry, 2022, 10: 821392.

    [21] Liang-Xiu Liao, Ze-Diao Huang, Fu-Ting Wei, Wen-Jing Wang*, Xiao-Long Yang*. New chromone analog and pyrrole alkaloid produced by Penicillium sclerotiorum and their antibacterial activity. Journal of Asian Natural Products Research, 2022, doi: /10.1080/10286020.2022.2084585.

    [22] Jing-Fang Xiao, Qing-Hua Ma, Rui-Li Cai, Jing-Ya Miao, Ze-Xuan Yan, Xiao-Long Yang*, Ye-Miao Chen*. Acute anti-cancer activity of crude extracts from two endophytic fungi Chaetomium cochliodes and Penicillium sp. in cancer cell lines and mice. International Journal of Pharmacology, 2022, 18: 1583-1592.

    [23] Jing Li, Sheng-Ping Jiang, Cheng-Yun Huang, Xiao-long Yang*. Atraric acid ameliorates hyperpigmentation through the down-regulation of MC1R/PKA/CREB signaling pathway. International Journal of Molecular Sciences, 2022. (In press)

    [24] Qing-Pei Liu, Si-Yu Zhong, Xin-Rui Wang, Shuai-Biao Gao, Xiao-Long Yang*, Fu-Sheng Chen*, István Molnár*. An integrated approach to determine the boundaries of the azaphilone pigment biosynthetic gene cluster of Monascus ruber M7 grown on potato dextrose agar. Frontiers in Microbiology, 2021, 12:680629.

    [25] Jun-Yan Qu, Cheng Zeng, Ting-Ting Zou, Xu Chen, Xiao-Long Yang*, Zheng-Hong Lin*. Autophagy induction by trichodermic acid attenuates endoplasmic reticulum stress-mediated apoptosis in colon. International Journal of Molecular Sciences, 2021, 22: 5566.

    [26] Qing-Lin Mou, Sheng-Xiang Yang, Ting-Xiang, Wen-Wen Liu, Jian Yang, Lan-Ping Guo*, Wen-Jing Wang*, and Xiao-Long Yang*. New cytochalasan alkaloids and cyclobutane dimer from an endophytic fungus Cytospora chrysosperma in Hippophae rhamnoides and their antimicrobial activities. Tetrahedron Letters, 2021, 87: 153207.

    [27] Peng-Jie Xian, Heng-Ye Chen, Zhang Feng*, Wei Zhao*, Xiao-Long Yang*. Capsulactone: a new 4-hydroxy-α-pyrone derivative from an endophytic fungus Penicillium capsulatum and its antimicrobial activity. Journal of Asian Natural Products Research, 2021, 23: 1100-1106.

    [28] Wen-Ting Zhao#, Xiong Shi#, Peng-Jie Xian, Zhang Feng*, Jian Yang*, Xiao-Long Yang*. A new fusicoccane diterpene and a new polyene from the plant endophytic fungus Talaromyces pinophilus and their antimicrobial activities. Natural Product Research, 2021, 35:124-130.

    [29] Ze-Diao Huang, Wen-Jing Wang, Xiao-Le Han*, Xiao-Long Yang*. Three new hydroxyphenylacetic acid derivatives and a new alkaloid from an endophytic fungus Mortierella sp. in Epimedium acuminatum Franch. and their antibacterial activity. Chemistry & Biodiversity, 2021, 18: e202100741.

    [30] Yong Xia*, Shu-Zhi Liu, Chang-Lin Li, Zhi-Ying Ai, Wen-Zhi Shen, Wen-Qi Ren, Xiao-Long Yang*. Discovery of a novel ferroptosis inducer - talaroconvolutin A - killing colorectal cancer cells in vitro and in vivo. Cell Death & Disease, 2020, 11:988.

    [31] Wen-Ting Zhao#, Qing-Pei Liu#, Heng-Ye Chen, Wei Zhao*, Yuan Gao*, Xiao-Long Yang*. Two novel eremophylane acetophenone conjugates from Colletotrichum gloeosporioides, an endophytic fungus in Salvia miltiorrhiza. Fitoterapia, 2020, 141: 104474.

    [32] Hai-Li Chen#, Wen-Ting Zhao#, Qing-Pei Liu, Heng-Ye Chen, Wei Zhao*, Deng-Feng Yang*, Xiao-Long Yang*. (±)-Preisomide: A new alkaloid featuring a rare naturally occurring tetrahydro-2H-1,2-oxazin skeleton from an endophytic fungus Preussia isomera by using OSMAC strategy. Fitoterapia, 2020, 141: 104475.

    [33] Sheng-Xiang Yang#, Jing-Fang Xiao#, Ting-Kai Liu, Ze-Diao Huang, Xiang Li, Ye-Miao Chen#, Xiao-Long Yang*. A 3D screening approach identifies the compound epitajixanthone hydrate as a new inhibitor of cancer cell growth and invasion. Anti-cancer Drugs, 2020, 31(9):890-899.

    [34] Xiao-Long Yang, Steffen Friedrich, Sen Yin, Oliver Piech, Katherine Williams, Thomas J. Simpson, Russell J. Cox*. Molecular basis of methylation and chain-length programming in a fungal iterative highly reducing polyketide synthase. Chemical Science, 2019, 10, 8478–8489.

    [35] Lu-Lin Xu#, Hai-Li Chen#, Ping Hai, Yuan Gao, Chuan-Dong Xie, Xiao-Long Yang*, Ikuro Abe*. (+)- and (?)-Preuisolactone A: A pair of caged norsesquiterpenoidal enantiomers with a tricyclo[4.4.01,6.02,8]decane carbon skeleton from the endophytic fungus Preussia isomera. Organic Letters, 2019, 21, 1078?1081.

    [36] Lu-Lin Xu, Ping Hai, Shuai-Bing Zhang, Jing-Fang Xiao, Yuan Gao, Bing-Ji Ma, Hai-Yan Fu*, Ye-Miao Chen*, Xiao-Long Yang*. Prenylated Indole Diterpene Alkaloids from a Mine Soil-derived Tolypocladium sp. Journal of Natural Products, 2019, 82: 221-231.

    [37] Heng-Ye Chen#, Ting-Kai Liu#, Jian Yang,* Xiao-Long Yang*. Emerones A-C: Three novel merosesquiterpenoids with unprecedented skeletons from Emericella sp. XL029. Organic & Biomolecular Chemistry, 2019, 17: 8450 -8455.

    [38] Sheng-Xiang Yang#, Wen-Ting Zhao#, Heng-Ye Chen, Lei Zhang, Ting-Kai Liu, He-Ping Chen*, Jian Yang*, Xiao-Long Yang*. Aureonitols A and B, two new C13-polyketides from Chaetomium globosum, an endophytic fungus in Salvia miltiorrhiza. Chemistry & Biodiversity, 2019, 16: e1900364.

    [39] Wei Zhao, Hai-Li Chen, Liu Hong, Xia Zhang, Xian-Jun Jiang, Dong-Lai Zhu*, Fei Wang*, Xiao-Long Yang*. Five new polyphenolic derivatives with antimicrobial activities from the root barks of Periploca sepium. Fitoterapia, 2019, 137: 104254.

    [40] Heng-Ye Chen, Ting-Kai Liu, Qiong Shi, Xiao-Long Yang*. Sesquiterpenoids and diterpenes with antimicrobial activity from Leptosphaeria sp. XL026, an endophytic fungus in Panax notoginseng. Fitoterapia, 2019, 137: 104243.

    [41] Lu-Lin Xu#, Xue-Jiao Pang#, Qiong Shi, Peng-Jie Xian, Yan-Duo Tao*, Xiao-Long Yang*. Two new prenylated indole diterpenoids from Tolypocladium sp. and their antimicrobial activities. Chemistry & Biodiversity, 2019, 16: e1900116.

    [42] Dan Xu, Xia Zhang, Xiong Shi, Peng-Jie Xian, Liu Hong, Yan-Duo Tao*, Xiao-Long Yang*. Two new cytochalasans from the marine sediment-derived fungus Westerdykella dispersa and their antibacterial activities. Phytochemistry Letters, 2019, 32: 52-55.

    [43] Xia Zhang#, Hai-Li Chen#, Liu Hong, Lu-Lin Xu, Xiao-Wei Gong, Dong-Lai Zhu, Xiao-Hua Xu, Wei Zhao*, Fei Wang*, Xiao-Long Yang*. Three new hopane-type triterpenoids from the aerial part of Adiantum capillus-veneris and their antimicrobial activities. Fitoterapia, 2019, 133: 146-149.

    [44] Ting Zhao, Lu-Lin Xu, Yan Zhang, Zheng-Hong Lin, Tao Xia, Deng-Feng Yang*, Ye-Miao Chen*, Xiao-Long Yang *. Three new α-pyrone derivatives from the plant endophytic fungus Penicillium ochrochloron and their antibacterial, antifungal and cytotoxic activities. Journal of Asian Natural Products Research, 2019, 21: 851-858.

    [45] Wei Zhao, Xiao-Wei Gong, Yuan-Xing Duan, Ji Yang, Xia Wu, Xian-Jun Jiang, Xiao-Hua Xu, Yong-Kuan Chen, Liu Yang*, Fei Wang*, Xiao-Long Yang*. Two new triterpenoids with antimicrobial activity from the leaves and twigs of Orophea yunnanensis. Natural Product Research, 2019, 33: 3472-3477.

  • 已獲授權專利

    [1] 楊小龍,時瓊,付海燕,楊天鳴. 一種基于量子點和納米金的賴氨酸檢測方法.授權日期:2019.12.24,授權專利號:ZL 201910104575.0,中國發明專利。

    [2] 夏勇,楊小龍. Talaroconvolutin A在抗癌藥物或食品中的應用. 授權日期:2021.06.29,授權專利號:ZL 202010549488.9,中國發明專利。

    [3] 陳葉苗,卞修武,肖靖芳,楊小龍,田甘,姚月良. 一種腫瘤細胞球的制備方法和應用. 授權日期:2020.03.31,授權專利號:ZL 201710962039.5,中國發明專利。

    [4] 楊小龍,牟青林,王文靜,向婷. 具有抗臨床耐藥性細菌功能的新型細胞松弛素及其制備方法. 授權日期:2022.10.21,授權專利號:ZL 202110385287.4,中國發明專利。

    [5] 楊小龍,時瓊,付海燕,楊天鳴. 一種納米卟啉催化劑及利用其催化TMB顯色的方法. 授權日期:2022.04.29,授權專利號:ZL 201910107765.8,中國發明專利。

    [6] 劉慶培,楊小龍,張丹,徐瑤. 聚酮合酶Preu3及其在制備2,4-二羥基-3,6-二甲基苯甲酸中的應用. 授權日期:2022.11.29,授權專利號: ZL 202110910678.3,中國發明專利。

    [7] 楊小龍,劉慶培,徐瑤,張丹. 聚酮合酶PreuA及其在制備紅粉苔酸中的應用. 授權日期:2022.11.29,授權專利號: ZL 202110820221.3,中國發明專利。

    [8] 楊小龍, 王森林, 劉文, 宋沙沙, 吳彥, 武紅帽. 一種茄鏈格孢菌及其應用. 授權日期:2023.04.28,申請號: ZL 202110950402.8,中國發明專利。

    [9] 楊小龍, 王森林, 劉文, 宋沙沙, 吳彥, 武紅帽. 一種細極鏈格孢菌株及其應用. 授權日期:2023.07.28,授權專利號: ZL 202110951437.3,中國發明專利。

    [10] 楊小龍, 王森林, 劉文, 宋沙沙, 吳彥, 武紅帽. 一種致密鏈格孢菌株及其應用. 授權日期:2023.04.28,授權專利號: ZL 202110956013.6,中國發明專利。

    [11] 楊小龍, 王森林, 劉文, 宋沙沙, 吳彥, 武紅帽. 一種蕓苔鏈格孢菌及其應用.授權日期:2023.03.07,授權專利號: ZL 202110957184.0,中國發明專利。

    [12] 楊小龍, 王森林, 劉文, 宋沙沙, 吳彥, 武紅帽. 一種棘孢曲霉菌及其應用. 授權日期:2023.09.22,授權專利號: ZL 202111500964.9,中國發明專利。

    [13] 楊小龍, 王森林, 劉文, 宋沙沙, 吳彥, 武紅帽. 一種黃曲霉菌及其應用. 授權日期:2023.09.22,授權專利號: ZL 202111501827.7,中國發明專利。

    [14] 劉慶培、楊小龍、徐瑤、張丹. 聚酮合酶PreuA-TEPreu3的構建及其在制備苔色酸中的應用. 授權日期:2023.03.24,授權專利號: 202110989776.0,中國發明專利。

    [15] 劉慶培, 楊小龍, 張丹, 徐瑤. 聚酮合酶Preu3-ΔCMeT及其在制備苔色酸中的應用. 授權日期:2023.04.28,授權專利號: 202111047088.9,中國發明專利。


作者:   責編:   審核:   上傳:

地址:中國-湖北-武漢 民族大道182號中南民族大學藥學院 郵編:430074
電話:027-67841196  Fax: 027-67841196
? 2016 中南民族大學藥學院

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