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吳濱

發(fā)布時間:2016-11-23 瀏覽次數(shù):

出生年月19733

民族:漢族

職稱:教授

學(xué)科專業(yè):有機(jī)化學(xué)

研究方向:有機(jī)合成化學(xué)和金屬有機(jī)化學(xué)

電話:15087127510

電子郵箱:2015084@mail.scuec.edu.cn


簡歷:教育背景和科研經(jīng)歷:

1994.91998.7 蘭州大學(xué)化學(xué)化工學(xué)院,學(xué)士

1998.92001.7 蘭州大學(xué)化學(xué)化工學(xué)院,碩士,導(dǎo)師:涂永強(qiáng)院士

2001.92004.7 中科院上海有機(jī)化學(xué)研究所博士,導(dǎo)師:麻生明院士

2004.82005.11美國內(nèi)布拉斯加州立大學(xué)林肯分校,博士后,導(dǎo)師:David B.Berkowitz 教授

2005.122010.8美國俄亥俄州立大學(xué),博士后,導(dǎo)師:T.V. RajanBabu 教授

2010.8-2015.6  中國科學(xué)院昆明植物研究所,研究員,博士生導(dǎo)師

2015.6-至今中南民族大學(xué)藥學(xué)院,教授,博士生導(dǎo)師


代表性研究成果

1.Yanli Xie, Dongdong Xu, Wen-Wu Sun, Shi-Jin Zhang, Xiao-Ping Dong, Bin Liu,* Yingbi Zhou,* Bin Wu*. Cobalt Catalyzed Oxidative Dimerization of 2-Phenylpyridine Derivatives . Asian J. Org. Chem. 2016, 5, 961.

2.Qun-Ying Yu, Hong-Ming Zhong, Wen-Wu Sun, Shi-Jin Zhang, Pei Cao,* Xiao-Ping Dong, Hong-Bo Qin, Ji-Kai Liu, Bin Wu*. Palladium-Catalyzed C(sp3)-H Functionalization at the C(3) Position of L-Pipecolinic Acid Derivatives. Asian J. Org. Chem. 2016, 5, 608.

3.Shi-Jin Zhang, Wen-Wu Sun, Pei Cao,* Xiao-Ping Dong,* Ji-Kai Liu, Bin Wu*. Stereoselective Synthesis of Diazabicyclic b-Lactams through Intramolecular Amination of Unactivated C(sp3)-H Bonds of Carboxamides by Palladium Catalysis. J. Org. Chem. 2016, 81, 956.

4.Pei Cao, Zhen-Jie Li, Wen-Wu Sun, Shashwat Malhotra, Yuan-Liang Ma, Bin Wu*, Virinder S. Parmar*. Cascade N-Alkylation/Hemiacetalization for FacileConstruction of the Spiroketal Skeleton of AcortatarinAlkaloids with Therapeutic Potentiality in DiabeticNephropathyNatural Products and Bioprospecting. 2015, 5, 37.

5.Wen-Wu Sun, Pei Cao, Ren-Qiang Mei, Yue Li, Yuan-Liang Ma, Bin Wu*. Palladium-Catalyzed Unactivated C(sp3)-H Bond Activation and Intramolecular Amination of Carboxamides: A New Approach to β-lactams. Org. Lett. 2014, 16, 480.

6.Bin Wu, Judith C. GalluccJon R. Parquette*, and T. V. RajanBabu*. Bimetallic catalysis in the highly enantioselective ring–opening reactions of aziridines. Chem. Sci., 2014, 5, 1102.

7.Bin Wu, Jon R. Parquette*, and T. V. RajanBabu*. Regiodivergent Ring Opening of Chiral Aziridines. Science. 2009, 326, 1662.

(This paper was highlighted by Chemistry World News and the website address iswww.rsc.org/chemistryworld/News/2009/December/17120903.asp.

This paper was highlighted by Chemical & Engineering News and the website address iswww.pubs.acs.org/cen/news/87/i51/8751notw4.html.)

8.Bin Wu, Judith C. Gallucci, Jon R. Parquette*, and T. V. RajanBabu*. Enantioselective Desymmetrization of meso-Aziridines with TMSN3 or TMSCN Catalyzed by Discrete Yttrium Complexes. Angew. Chem. Int. Ed. 2009, 48, 1126. (highlighted by inside cover and review paper: Angew. Chem. Int. Ed. 2009, 48, 2082.)

9.Nicola J. Baxter, Matthew W. Bowler, Tooba Alizadeh, Matthew J. Cliff, Andrea M. Hounslow, Bin Wu, David B. Berkowitz, Nicholas H. Williams, Steven J. Gamblin, G. Michael Blackburn,* and Jonathan P. Waltho.* Atomic details of near-transition state conformersfor enzyme phosphoryl transfer revealedby MgF3? rather than by phosphoranes.Proc. Natl. Acad. Sci.U.S.A. 2010, 107, 4555.

10.David B. Berkowitz*, Bin Wu, and Huijie Li. A Formal [3,3]-sigmatropic Rearrangement Route to Quaternary a-Vinyl Amino Acids: Use of Allylic N-PMP Trifluoroacetimidates. Org.Lett. 2006, 8, 971.

11.Shengming Ma*, Bin Wu, Xuefeng Jiang, and Shimin Zhao. Studies on Pd (II)-Catalyzed Synthesis of (Z)-a-Haloalkylidene-b-lactones from Cyclocarbonylation of 2-Alkynols and the Subsequent Coupling Reactions. J. Org. Chem. 2005, 70, 2568.

12.Shengming Ma*, Bin Wu, and Xuefeng Jiang. PdCl2-Catalyzed Efficient Transformation of Propargylic Amines to (E)-a-Chloroalkylidene-b-lactams. J. Org. Chem. 2005, 70, 2588.

13.Shengming Ma*, Bin Wu, and Zhangjie Shi. An Efficient Synthesis of 4-Halo-5-hydroxyfuran-2(5H)-ones via the Sequential Halolactonization and g-Hydroxylation of 4-Aryl-2,3-alkadienoic Acids. J. Org. Chem. 2004, 69, 1429.

14.Shengming Ma*, Bin Wu, and Shimin Zhao. A Mild and Efficient Synthesis of (Z)-a-Chloroalkylidene-b-lactones via the PdCl2-Catalyzed Cyclocarbonylation of 2-Alkynols. Org.Lett. 2003, 5, 4429.

15.Yan Xing Jia, Bin Wu, Xin Li, Shi Kuo Ren, Yong Qiang Tu,* Albert S. C. Chen, and William Kitching. Synthetic Studies of the HIV-1 Protease Inhibitive Didemnaketals: Stereocontrolled Synthetic Approach to the Key Mother Spiroketals. Org.Lett. 2001, 3, 847.

16.Xin Li, Bin Wu, Xue Zhi Zhao, Yan Xing Jia, Yong Qiang Tu,* De Run Li. An Interesting AlEt3-Promoted Stereoselective Tandem Rearrangement / Reduction of a-Hydroxy (or Amino) Heterocyclopane. Synlett., 2003, 623.

17.Yan Xing Jia, Xin Li, Bin Wu, Xue Zhi Zhao, and Yong Qiang Tu.* A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals. Tetrahedron, 2002, 58, 1697.


授權(quán)專利

1.吳濱、孫文武、曹沛、趙金華、楊蓮。N-喹啉基取代的?-內(nèi)酰胺類化合物,其合成方法和以該類化合物為活性成分的藥物組合物及其應(yīng)用,專利號:ZL 201310428596.0

2. 吳濱、孫文武。順式稠環(huán)的?-內(nèi)酰胺化合物的合成方法,專利號:ZL 201310549472.8


獲獎:

2011 入選“云南省高端科技人才引進(jìn)計劃”


作者:   責(zé)編:   審核:   上傳:

地址:中國-湖北-武漢 民族大道182號中南民族大學(xué)藥學(xué)院 郵編:430074
電話:027-67841196  Fax: 027-67841196
? 2016 中南民族大學(xué)藥學(xué)院

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