出生年月：1973年3月

民族：漢族

職稱：教授

學科專業：有機化學

研究方向：有機合成化學和金屬有機化學

電話：15087127510

電子郵箱：2015084@mail.scuec.edu.cn

簡歷：教育背景和科研經歷：

1994.9－1998.7 蘭州大學化學化工學院，學士

1998.9－2001.7 蘭州大學化學化工學院，碩士，導師：涂永強院士

2001.9－2004.7 中科院上海有機化學研究所, 博士，導師：麻生明院士

2004.8－2005.11美國內布拉斯加州立大學林肯分校，博士后，導師：David B.Berkowitz 教授

2005.12－2010.8美國俄亥俄州立大學，博士后，導師：T.V. RajanBabu 教授

2010.8-2015.6  中國科學院昆明植物研究所，研究員，博士生導師

2015.6-至今中南民族大學藥學院，教授，博士生導師

代表性研究成果

1.Yanli Xie, Dongdong Xu, Wen-Wu Sun, Shi-Jin Zhang, Xiao-Ping Dong, Bin Liu,^* Yingbi Zhou,^* Bin Wu^*. Cobalt Catalyzed Oxidative Dimerization of 2-Phenylpyridine Derivatives . Asian J. Org. Chem. 2016, 5, 961.

2.Qun-Ying Yu, Hong-Ming Zhong, Wen-Wu Sun, Shi-Jin Zhang, Pei Cao,* Xiao-Ping Dong, Hong-Bo Qin, Ji-Kai Liu, Bin Wu*. Palladium-Catalyzed C(sp³)-H Functionalization at the C(3) Position of L-Pipecolinic Acid Derivatives. Asian J. Org. Chem. 2016, 5, 608.

3.Shi-Jin Zhang, Wen-Wu Sun, Pei Cao,^* Xiao-Ping Dong,^* Ji-Kai Liu, Bin Wu^*. Stereoselective Synthesis of Diazabicyclic b-Lactams through Intramolecular Amination of Unactivated C(sp³)-H Bonds of Carboxamides by Palladium Catalysis. J. Org. Chem. 2016, 81, 956.

4.Pei Cao, Zhen-Jie Li, Wen-Wu Sun, Shashwat Malhotra, Yuan-Liang Ma, Bin Wu*, Virinder S. Parmar*. Cascade N-Alkylation/Hemiacetalization for FacileConstruction of the Spiroketal Skeleton of AcortatarinAlkaloids with Therapeutic Potentiality in DiabeticNephropathy. Natural Products and Bioprospecting. 2015, 5, 37.

5.Wen-Wu Sun, Pei Cao, Ren-Qiang Mei, Yue Li, Yuan-Liang Ma, Bin Wu*. Palladium-Catalyzed Unactivated C(sp³)-H Bond Activation and Intramolecular Amination of Carboxamides: A New Approach to β-lactams. Org. Lett. 2014, 16, 480.

6.Bin Wu, Judith C. Gallucc, Jon R. Parquette*, and T. V. RajanBabu*. Bimetallic catalysis in the highly enantioselective ring–opening reactions of aziridines. Chem. Sci., 2014, 5, 1102.

7.Bin Wu, Jon R. Parquette*, and T. V. RajanBabu*. Regiodivergent Ring Opening of Chiral Aziridines. Science. 2009, 326, 1662.

(This paper was highlighted by Chemistry World News and the website address iswww.rsc.org/chemistryworld/News/2009/December/17120903.asp.

This paper was highlighted by Chemical & Engineering News and the website address iswww.pubs.acs.org/cen/news/87/i51/8751notw4.html.)

8.Bin Wu, Judith C. Gallucci, Jon R. Parquette*, and T. V. RajanBabu*. Enantioselective Desymmetrization of meso-Aziridines with TMSN₃ or TMSCN Catalyzed by Discrete Yttrium Complexes. Angew. Chem. Int. Ed. 2009, 48, 1126. (highlighted by inside cover and review paper: Angew. Chem. Int. Ed. 2009, 48, 2082.)

9.Nicola J. Baxter, Matthew W. Bowler, Tooba Alizadeh, Matthew J. Cliff, Andrea M. Hounslow, Bin Wu, David B. Berkowitz, Nicholas H. Williams, Steven J. Gamblin, G. Michael Blackburn,* and Jonathan P. Waltho.* Atomic details of near-transition state conformersfor enzyme phosphoryl transfer revealedby MgF₃^? rather than by phosphoranes.Proc. Natl. Acad. Sci.U.S.A. 2010, 107, 4555.

10.David B. Berkowitz*, Bin Wu, and Huijie Li. A Formal [3,3]-sigmatropic Rearrangement Route to Quaternary a-Vinyl Amino Acids: Use of Allylic N-PMP Trifluoroacetimidates. Org.Lett. 2006, 8, 971.

11.Shengming Ma*, Bin Wu, Xuefeng Jiang, and Shimin Zhao. Studies on Pd (II)-Catalyzed Synthesis of (Z)-a-Haloalkylidene-b-lactones from Cyclocarbonylation of 2-Alkynols and the Subsequent Coupling Reactions. J. Org. Chem. 2005, 70, 2568.

12.Shengming Ma*, Bin Wu, and Xuefeng Jiang. PdCl₂-Catalyzed Efficient Transformation of Propargylic Amines to (E)-a-Chloroalkylidene-b-lactams. J. Org. Chem. 2005, 70, 2588.

13.Shengming Ma*, Bin Wu, and Zhangjie Shi. An Efficient Synthesis of 4-Halo-5-hydroxyfuran-2(5H)-ones via the Sequential Halolactonization and g-Hydroxylation of 4-Aryl-2,3-alkadienoic Acids. J. Org. Chem. 2004, 69, 1429.

14.Shengming Ma*, Bin Wu, and Shimin Zhao. A Mild and Efficient Synthesis of (Z)-a-Chloroalkylidene-b-lactones via the PdCl₂-Catalyzed Cyclocarbonylation of 2-Alkynols. Org.Lett. 2003, 5, 4429.

15.Yan Xing Jia, Bin Wu, Xin Li, Shi Kuo Ren, Yong Qiang Tu,* Albert S. C. Chen, and William Kitching. Synthetic Studies of the HIV-1 Protease Inhibitive Didemnaketals: Stereocontrolled Synthetic Approach to the Key Mother Spiroketals. Org.Lett. 2001, 3, 847.

16.Xin Li, Bin Wu, Xue Zhi Zhao, Yan Xing Jia, Yong Qiang Tu,* De Run Li. An Interesting AlEt₃-Promoted Stereoselective Tandem Rearrangement / Reduction of a-Hydroxy (or Amino) Heterocyclopane. Synlett., 2003, 623.

17.Yan Xing Jia, Xin Li, Bin Wu, Xue Zhi Zhao, and Yong Qiang Tu.* A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals. Tetrahedron, 2002, 58, 1697.

授權專利

1.吳濱、孫文武、曹沛、趙金華、楊蓮。N-喹啉基取代的?-內酰胺類化合物，其合成方法和以該類化合物為活性成分的藥物組合物及其應用，專利號：ZL 201310428596.0

2. 吳濱、孫文武。順式稠環的?-內酰胺化合物的合成方法，專利號：ZL 201310549472.8

獲獎：

2011 入選“云南省高端科技人才引進計劃”