出生年月:1990年10月
民族:漢族
職稱:副教授/碩士生導師
學科專業:藥物分析;化學計量學
研究方向:食藥安全的可視化陣列傳感分析
電子郵箱:chenhengye@126.com
? 教育及工作經歷:
2024/03 - 至今 中南民族大學,藥學院,副教授
2018/07 - 2024/03 中南民族大學,藥學院,講師
2016/10 - 2017/10 瑞士日內瓦大學,聯合培養博士,導師:Fran?ois Barja
2012/09 - 2018/06 華中農業大學,食品科學技術學院,博士,導師:陳福生 教授
2008/09 - 2012/06 華中農業大學,食品科學技術學院,學士
? 教學工作:
承擔和參與多門課程教學,本科生課程:《藥學儀器分析(B)》、《藥物分析信息學》、《藥學儀器分析實驗》等;研究生課程:《現代中藥分析學》、《中藥學及民族藥學專論》等。獲批校級教研項目1項,參編中藥材安全檢測和藥食兩用植物資源相關學術著作6部,發表教研論文1篇;指導多名本科生在本領域權威SCI期刊發表學術論文,并獲校級優秀學士學位論文。
? 社會兼職:
J. Food. Quality 客座編輯;中國民族醫藥學會健康產業分會理事,湖北省生物工程學會會員,湖北省植物學會會員,阿拉山口市金陸工程項目管理有限公司科技創新版塊專家顧問。
? 科研項目:
1. 國家自然科學基金委員會,面上項目,熱加工食品中結合態晚期糖基化產物的原位識別和動態減控機制研究,202401-202712,50萬,主持;
2. 國家自然科學基金委員會,青年項目,吡嗪類化合物靶向陣列傳感器構建及對高溫大曲白酒的精準鑒別,202101-202312,24萬,主持;
3. 江蘇省市場監督管理局,科技計劃項目,可視化陣列傳感結合化學計量學對濃香型白酒真實性的免儀器鑒別研究,202401-202512,12萬,主持;
4. 江蘇省市場監督管理局,科技計劃項目,金屬離子介導的可視化陣列傳感對濃香型白酒真實性的精準鑒別,202301-202501,12萬,主持;
5. 中南民族大學引進人才項目,納米效應多元光譜傳感對中國白菊中農殘的快速識別機制研究,202204-202503,5萬,主持;
6. 中央高校基本科研業務費專項資金項目,基于可視化陣列傳感器的術類藥材特征成分免儀器快檢技術研究,202304-202604,5萬,主持;
7. 國家重點研發計劃,食品營養與安全關鍵技術研發重點專項,課題二子課題:風險因子靶向吸附消減技術研究,202312-202712,95萬,參與(骨干);
8. 國家重點研發計劃,“中醫藥現代化”重點專項,課題二:基于土壤特征的道地藥材品質形成機制研究,202010-202209,2584萬元,參與(骨干);
9. 國家自然科學基金委員會,面上項目,納米效應陣列紙傳感器構建及對蔬菜中內吸性農殘精準識別機制研究,202001-202312,58萬,參與(骨干);
10. 橫向課題,化妝品中重金屬Pb檢出技術開發,202212-202312,6萬,主持;
11. 橫向課題,植物源食品安全快檢及真實性溯源實驗裝備,202312-202412,35萬,參與(排第2);
12. 橫向課題,化妝品中原料成分質量控制快檢方法,202212-202312,30萬,參與(排第2);
13. 橫向課題,濃香型白酒產地特征量子點芯片指紋圖譜技術研發與集成,201907-202207,50萬,參與(排第2);
14. 中南民族大學教研項目,大數據時代下藥物分析信息學課程的教學方法改革研究,202206-202406,1萬,主持。
? 代表性論文:
[1] Chen Hengye#, Ren Lixue#, Yang Yinan, Long Wanjun, Lan Wei, Yang Jian, Fu Haiyan*. Three-dimensional fluorescence combined with alternating trilinear decomposition and random forest algorithm for the rapid prediction of species, geographical origin and main components of Glycyrrhizae Radix et Rhizoma (Gancao), Food Chemistry, 2024,444: 138603.
[2] Lei Guanghua, Guan Yuting Guan, Long Wangjun, Lan Wei, Hu Zikang, Bai Xiuyun, Huang Yun, Yang Jian Yang, Chen Hengye*, Fu Haiyan*. Prediction of Active Compound Content and Identification of Origin of Chrysanthemi Flos using Fe3+-mediated Multi-Mechanism Fluorescence Visual Sensor with Chemometrics, Sensors and actuators B: chemical, 2023, 399: 134793.
[3] Zhu Yanmei#, Xiang Fushuang#, Su Yuanyuan, Jiang Xue, Cang Yipeng, Long Wanjun, Lan Wei, Deng Gaoqiong, Chen Hengye *, She Yuanbin*, Fu Haiyan*. Authenticity identification of high-Temperature Daqu Baijiu through multi-channel visual array sensor of organic dyes combined with smart phone App. Food Chemistry, 2023, 438:137980.
[4] Chen Hengye#, Zhu Yanmei#, Xie Yufei, Long Wanjun, Lan wei, She Yuanbin, Fu Haiyan*. Rapid identification of high-temperature Daqu Baijiu with the same aroma type through the excitation emission matrix fluorescence of maillard reaction products. Food Control. 2023, 153: 109938.
[5] Deng Gaoqiong #, Chen Hengye #, Shi Qiong, Ren Lixue, Liang Ke, Long Wanjun, Lan Wei, Han Xiaole*, She Yuanbin, Fu Haiyan*. Colorimetric assay based on peroxidase-like activity of dodecyl trimethylammonium bromide-tetramethyl zinc (4-pyridinyl) porphyrin for detection of organophosphorus pesticides. Microchimica Acta, 2022, 189(10): 375.
[6] Liu Rui, Chen Hengye, Bai Xiuyun, Huang Yun, Li Huiling, Long Wanjun, Lan Wei, She Yuanbin, Fu Haiyan*. Visual classification for sesame oil adulteration detection and quantification of compounds used as adulterants using flavor compounds targeted array sensor in combination with DD-SIMCA and PLS. Sensors and Actuators B: Chemical. 2022, 357: 131335.
[7] Liu Rui#, Chen Hengye#, Wang Shuo, Wei Liuna, Yu Yongjie, Lan Wei, Fu Haiyan*, Yang Jian*, Guo Lanping*. Maillard reaction products and Guaiacol as production process and raw material markers for the authenticity identification of sesame oil. Journal of the Science of Food and Agriculture. 2022, 102:250-258.
[8] Wu Meixia, Chen Hengye, Fan Yao, Wang Songtao, Hu Ying, Liu Jian, Shen Caihong, Zhou Chunsong, Fu Haiyan*, She Yuanbin*. Carbonyl flavor compound-targeted colorimetric sensor array based on silver nitrate and o-phenylenediamine derivatives for the discrimination of Chinese Baijiu. Food Chemistry. 2022, 372: 131216.
[9] Chen Hengye#, Shi Qiong#, Deng gaoqiong, Chen Xiahe, Yang Yunfang, Lan Wei, Hu Ying, Zhang Lei, Xu Lu, Li Chunyuan, Zhou Chunsong, She Yuanbin, Fu Haiyan*. Rapid and highly sensitive colorimetric biosensor for the detection of glucose and hydrogen peroxide based on nanoporphyrin combined with bromine as a peroxidase-like catalyst. Sensors and Actuators B: Chemical. 2021, 343: 130104.
[10] Chen Hengye#, Zhang Lei#, Hu Ying, Zhou Chunsong, Lan Wei, Fu Haiyan*, She Yuanbin*. Nanomaterials as optical sensors for application in rapid detection of food contaminants, quality and authenticity. Sensors and Actuators B: Chemical. 2021, 329: 129135.
[11] Wang Shou#, Chen Hengye#, Xie Hongliang, Wei Liuna, Xu Lu, Zhang Lei, Lan Wei, Zhou Chunsong, She Yuanbin, Fu Haiyan*. A novel thioctic acid-carbon dots fluorescence sensor for the detection of Hg2+ and thiophanate methyl via S-Hg affinity. Food Chemistry. 2021, 346: 128923.
[12] Chen Hengye#, Liu Rui#, Guo Xiaoming, Deng Gaoqiong, Xu Lu, Zhang Lei, Lan Wei, Zhou Chunsong, She Yuanbin, Fu Haiyan*. Visual paper-based sensor for the highly sensitive detection of caffeine in food and biological matrix based on CdTe-nano ZnTPyP combined with chemometrics. Microchimica Acta. 2021, 188: 27.
[13] Chen Hengye#, Wei Liuna#, Guo Xiaoming, Hai Chengying, Xu Lu, Zhang Lei, Lan Wei, Zhou Chunsong, She Yuanbin, Fu Haiyan*. Determination of L-theanine in tea water using fluorescence-visualized paper-based sensors based on CdTe quantum dots/corn carbon dots and nano-porphyrin with chemometrics. Journal of the Science of Food and Agriculture. 2021, 101: 2552-2560.
[14] Wei Liuna#, Chen Hengye#, Liu Rui, Wang Shuo, Liu Tingkai, Hu Zikang, Lan Wei, Yu Yongjie*, She Yuanbin, Fu Haiyan*. Fluorescent sensor based on quantum dots and nano porphyrin for highly sensitive and specific recognition of ethyl carbamate in fermented food. Journal of the Science of Food and Agriculture, 2021, 101:6193.
[15] Chen Hengye#, Hu Ou#, Fan Yao, Xu Lu, Zhang Lei, Lan Wei, Hu Ying, Xie Xingrui, Ma Lixia, She Yuanbin, Fu Haiyan*. Fluorescence paper-based sensor for visual detection of carbamate pesticides in food based on CdTe quantum dot and nano ZnTPyP. Food Chemistry. 2020, 327: 127075.
[16] Chen Hengye#, Shi Qiong#, Fu Haiyan*, Hu Ou, Fan Yao, Xu Lu, Zhang Lei, Lan Wei, Sun Donglei, Yang Tianming, She Yuanbin *. Rapid detection of five pesticide residues using complexes of gold nanoparticle and porphyrin combined with ultraviolet visible spectrum. Journal of the Science of Food and Agriculture. 2020, 100(12): 4464-4473.
[17] Chen Hengye#, Wang Shuo#, Fu Haiyan*, Chen Fusheng, Zhang Lei, Lan Wei, Yang Jian, Yang Xiaolong, She Yuanbin. A colorimetric sensor array for recognition of 32 Chinese traditional cereal vinegars based on “turn-off/on” fluorescence of acid-sensitive quantum dots. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 227: 117683.
[18] Chen Hengye#, Wang Shuo#, Fu Haiyan*, Xie Hongliang, Lan Wei, Xu Lu, Zhang Lei, She Yuanbin*. Dual-QDs ratiosfluorescent probe for sensitive and selective detection of silver ions contamination in real sample. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 234: 118248.
[19] Chen Hengye#, Hu Ou#, Fu Haiyan*, Fan Yao, Xu Lu, Meng Qingjun, Zhang Lei, Lan Wei, Wu Chunying, Tang Siyi, She Yuanbin*. Paper-based sensor for visual detection of Ag+ based on a “turn-off-on” fluorescent design. Microchemical Journal, 2020: 157: 104887.
[20] Chen Hengye, Chen Tao, Giudici Paolo, Chen Fusheng*. Vinegar Functions on Health: Constituents, Sources, and Formation Mechanisms. Comprehensive Reviews in Food Science and Food Safety, 2016, 15(6): 1124-1138.
? 代表性專利:
[1] 陳亨業,朱艷美,付海燕,佘遠斌,龍婉君,蘭薇.一種基于美拉德反應產物熒光信號解析的高溫大曲白酒鑒別和化合物預測方法.中國發明專利,ZL 202310400903.8 (已授權).
[2] 付海燕,陳亨業,王碩,佘遠斌.一種基于量子點熒光猝滅的仿生陣列傳感器及其應用.中國發明專利,ZL 201910095806.6 (已授權).
[3] 陳福生,陳亨業.一株高產苯乳酸的葡糖醋桿菌及其苯乳酸的制備方法.中國發明專利,Z L201610853578.0 (已授權).
[4] 付海燕,韋柳娜,陳亨業,蘭薇,佘遠斌.一種用于淀粉類摻假判別的碳量子點熒光傳感方法.中國發明專利.ZL 202010483828.2(已授權).
[5] 付海燕,韋柳娜,陳亨業,時瓊,蘭薇,佘遠斌.一種鄰苯二甲酸二(2-乙基己基)酯的快速比色檢測法.中國發明專利.ZL 202010443474.9(已授權).
[6] 付海燕,劉瑞,陳亨業,蘭薇,佘遠斌. 一種快速檢測食品中白藜蘆醇的方法. 中國發明專利. ZL 202010618266.8(已授權).
[7] 付海燕,劉瑞,陳亨業,蘭薇,佘遠斌. 一種快速定量測定pH值和/或尿酸的方法. 中國發明專利,專利號:ZL 202010862685.6(已授權).
[8] 付海燕,鄧高瓊,韋柳娜,王碩,陳亨業,佘遠斌,周春松. 基于納米金蝕刻檢測農藥甲萘威的方法. 中國發明專利, 專利號:ZL 202110440927.7(已授權)
[9] 付海燕,王碩,陳亨業,鄧高瓊,劉庭愷,蘭薇,佘遠斌. 一種快速檢測汞離子或甲基硫菌靈的方法. 中國發明專利,專利號:ZL 202011478158.1(已授權)
[10] 付海燕,韋柳娜,陳亨業,鄧高瓊,蘭薇,佘遠斌. 一種圓片狀四-(4-苯基)鋇納米卟啉熒光探針及利用其檢測殺螟丹的方法. 中國發明專利,專利號:ZL 202011479881.1(已授權).
[11] 付海燕,劉瑞,陳亨業,楊健,王游游,周春松,佘遠斌. 一種檢測芝麻油摻假的方法. 中國發明專利 專利號:ZL 202110760920.3(已授權).
[12] 付海燕,王碩,時瓊,陳亨業,蘭薇,佘遠斌. 一種基于碳點-量子點比率熒光傳感器的制備方法及其應用. 中國發明專利,專利號:ZL 202010358457.5 (已授權).
[13] 付海燕,韋柳娜,陳亨業,佘遠斌. 一種用于實時檢測水環境中有害物質的裝置. 中國實用新型專利,申請號:202021712240.1, 專利號:ZL 202021712240.1(已授權)..
[14] 付海燕,韋柳娜,陳亨業,王碩,周春松,佘遠斌. 一種比色檢測裝置. 中國實用新型專利,申請號:202120325824.1, 申請日:2021-02-04, 專利號:ZL 202120325824.1 (已授權).
[15] Haiyan Fu, Jian Yang, Xiaolong Yang, Yuanbin She, Hengye Chen, Wanjun Long, Shuo Wang, Xueqing Zeng, Xiuyun Bai, Method for Identifying Origin of Chrysanthemi Flos. US 11567009 B1,2023-01-31(已授權,美國發明專利)
? 代表性軟著:
[1] 陳亨業,付海燕,佘遠斌,朱艷美,龍婉君,蘭薇. 白酒可視化傳感鑒別微信小程序. 軟件著作,登記號:2023SR1480679, 2023-11-21.
[2] 付海燕,陳亨業,楊健,龍婉君,蘭薇. 不同產地和品種中國白菊農藥殘留查詢系統. 軟件著作,登記號:2022SR1535963, 2022-11-18.
[3] 付海燕,楊健,陳亨業,龍婉君,楊小龍,蘭薇. 百合品質的熒光可視化表征軟件V1.0. 軟件著作,登記號:2022SR1535808, 2022-11-18.
[4] 付海燕,楊健,龍婉君,楊小龍,陳亨業. 百合納米效應紅外光譜表征軟件. 軟件著作,登記號:2022SR0186341, 2021-12-01.
[5] 付海燕,楊健,陳亨業,龍婉君,楊小龍. 百合品質形成及其成分因子協同貢獻查詢系統. 軟件著作,登記號:2022SR0186339, 2021-12-01.
[6] 付海燕,楊健,楊小龍,陳亨業,蘭薇. 白菊品質可視化傳感比色表征軟件. 軟件著作,登記號:2021SR1348957, 2021-07-12.
[7] 付海燕,楊健,楊小龍,陳亨業,蘭薇. 菊花特征品質因子與土壤礦質元素關聯性分析系統. 軟件著作,登記號:2021SR1348932, 2021-07-12.
? 代表性專著
[1] 陳亨業(參編). 民族植物資源化學與生物活性研究. 北京: 化學工業出版社, 2022.06.
[2] 陳亨業(參編). 醋酸菌研究與應用. 北京: 化學工業出版社, 2022.04.
[3] 陳亨業(參編). 中藥材重金屬研究及國際標準制定. 北京: 中國中藥出版社, 2023.07.
[4] 陳亨業(參編). 中藥材農藥殘留研究及國際標準制定. 北京: 中國中藥出版社, 2023.08.
[5] 陳亨業(參編). 中藥材二氧化硫研究及國際標準制定. 北京: 中國中藥出版社, 2023.09.
[6] 陳亨業(參編). 武陵山區藥用及食用植物資源-湖北冊. 化學工業出版社, 2023.11.