
姓名:程崟家
職稱:副教授
單位:中南民族大學化學與材料科學學院
學科專業:高分子化學和物理
研究方向:生物醫用高分子材料
學者簡介:
程崟家(1988-),女,博士,副教授。2011年畢業于南華大學,獲得化工制藥專業學士學位;2011-2016年在武漢大學化學與分子科學學院碩博連讀,獲高分子化學與物理專業博士學位。2016年8月起,于中南民族大學化學與材料科學學院工作。主要從事功能性納米材料的設計、構建及其在生物醫學方面的應用研究。已在Biomaterials、Journal of Controlled Release; ACS Applied Materials & Interfaces、Polymer Chemistry、ACS Biomaterials Science & Engineering等國際SCI刊物上公開發表論文二十余篇;申請國家發明專利4項,授權3項;長期擔任Adv. Sci., Adv. Funct. Mater., Acta Biomater., J. Mater. Chem. B, 等國際期刊的獨立審稿人。
主持的科研項目
1. 國家自然科學基金面上項目(52472291),基于可降解介孔納米復合物構筑智能型仿生納米平臺用于三陰性乳腺癌診療一體化研究,2025-2028。
2. 國家自然科學基金面上項目(52173295),“特洛伊木馬”型仿生納米復合材料的構建及在腫瘤多模態精準診療中的應用,2022-2025。
3.國家自然科學基金青年項目(51703251),多功能富勒烯/介孔硅復合納米藥物控釋系統的構建及其腫瘤診療的研究,2018-2020。
已授權專利
1.程崟家,秦四勇,張愛清。一種聚集誘導發光多肽膠束型診斷試劑及其在近紅外區域生物成像中的應用,2022.0.17,中國,ZL202110709792.X。
2.程崟家,黎永秀,秦四勇,張愛清。一種酶敏感型多肽膠束型診斷試劑及其在制備抗腫瘤藥物中的應用,2022.05.30,中國,ZL202110540998.4。
3.程崟家,余金鑫,曾方宇,劉強宇,張愛清。一種紅細胞膜仿生修飾的“核-殼”型納米復合材料的制備方法及其應用,2024.08.09, 中國, ZL 2024 1 0210240.8。
近年來發表的部分論文
1. Feng J.Q.#, Tian X.#, Cao R.G.#, Li Y.X., Liu W.L., Huang R.*, Qin S.Y.*, Zhang A.Q.*, Cheng Y.J. * An AIE-based theranostic nanoplatform for enhanced colorectal cancer therapy: Real-time tumor-tracking and chemical-enhanced photodynamic therapy. Chin. Chem. Lett., 2024, 35(12): 109657.
2. He Y., Chen Q.W., Yu J. X., Qin S. Y., Liu W. L., Ma Y. H., Chen X. S., Zhang A. Q., Zhang X. Z., Cheng Y. J.* Yeast cell membrane-camouflaged PLGA nanoparticle platform for enhanced cancer therapy. J Control Release, 2023, 359: 347-358.
3. Cheng Y. J.*, Qin S. Y., Liu W L, et al. Dual-Targeting Photosensitizer-Peptide Amphiphile Conjugate for Enzyme-Triggered Drug Delivery and Synergistic Chemo-Photodynamic Tumor Therapy. Adv. Mater. Interfaces, 2020, 7(19): 2000935. (Inside Cover)
4. Cheng Y. J. *, Hu J. J., Qin S. Y., et al. Recent advances in functional mesoporous silica-based nanoplatforms for combinational photo-chemotherapy of cancer. Biomaterials, 2020, 232, 119738.
5. Cheng Y. J. *, Qin S. Y., Ma Y. H., et al. Super-pH-Sensitive Mesoporous Silica Nanoparticle-Based Drug Delivery System for Effective Combination Cancer Therapy. ACS Biomaterials Science & Engineering, 2019, 5 (4), 1878-1886.
6. Cheng Y. J. *, Zhang A. Q., Hu J. J., et al. Multifunctional Peptide-Amphiphile End-Capped Mesoporous Silica Nanoparticles for Tumor Targeting Drug Delivery. ACS Applied Materials & Interfaces, 2017, 9, 2093-2103.
7. Cheng Y. J., Luo G. F., Zhu J. Y., et al. Enzyme-induced and tumor-targeted drug delivery system based on multifunctional mesoporous silica nanoparticles. ACS Applied Materials & Interfaces, 2015, 7, 9078-9087.
8. Cheng Y. J., Cheng H., Zhao X., et al. Self-assembled micelles of a multi-functional amphiphilic fusion (MFAF) peptide for targeted cancer therapy. Polymer Chemistry, 2015, 6, 3512-3520.
9. Xu X. D.#, Cheng Y. J. # (共同第一作者), Wu J., et al. Smart and hyper-fast responsive polyprodrug nanoplatform for targeted cancer therapy. Biomaterials, 2015, 76, 238-249.
10. Cheng Y. J., Zeng X., Cheng D. B., et al. Functional mesoporous silica nanoparticles (MSNs) for highly controllable drug release and synergistic therapy. Colloids and Surfaces B: Biointerfaces, 2016, 145, 217-225.
通訊地址:武漢市洪山區民族大道182號
E-mail:Chengyj@mail.scuec.edu.cn