姓名:劉新瓊
職務(wù)/職稱:教授
研究方向:植物遺傳學(xué)
通訊地址:中南民族大學(xué)生命科學(xué)學(xué)院3樓B區(qū)305室
聯(lián)系電話:027-67842689
Email:liuxinqiong@mail.scuec.edu.cn
一、學(xué)習(xí)及工作經(jīng)歷
1、1990.9-1994.7:湖北農(nóng)學(xué)院(現(xiàn)長江大學(xué))植物保護專業(yè),獲農(nóng)學(xué)學(xué)士學(xué)位
2、1994.9-1997.6:華中農(nóng)業(yè)大學(xué)植物病理學(xué)專業(yè),獲農(nóng)學(xué)碩士學(xué)位
3、2002.9-2005.6:華南農(nóng)業(yè)大學(xué)分子植物病理學(xué)專業(yè),獲農(nóng)學(xué)博士學(xué)位
4、1997.7-2002.8:長江蔬菜雜志社任科技編輯
5、2009.10-2011.10:日本農(nóng)業(yè)生物資源研究所JSPS博士后
6、2005.7-至今:中南民族大學(xué)生命科學(xué)學(xué)院從事教學(xué)和科研工作
二、科研活動及成果
(一)主要研究方向
1、聚焦植物誘導(dǎo)抗病基因的挖掘與分子機理研究。
2、植物源提取液的抑菌篩選及作用機理研究。
(二)主持的科研項目
1、2022.11-2025.12, 浙江溫嶺和泰水產(chǎn)有限公司,HZY22119,甲殼類廢棄物提煉生物活性物質(zhì)的研究及開發(fā)。
2、2023.10.01-2024.9.30,環(huán)境有害微生物檢測技術(shù)研發(fā),北京新豪世紀科技發(fā)展有限公司,HZY23113。
3、2014.01-2017.12,國家自然科學(xué)基金面上項目,31370306,水楊酸應(yīng)答新基因OsAAA-ATPase-1在水稻廣譜抗病反應(yīng)中的分子機理研究。
4、2014.01-2016.12,湖北省自然科學(xué)基金重點項目,2013CFA098,利用廣譜抗性相關(guān)基因OsAAA-ATPase-1創(chuàng)制水稻抗病性新材料。
5、2014.01-2016.12,國家重大項目轉(zhuǎn)基因?qū)m?子課題),2014ZX0800904B,稻瘟病廣譜抗性基因的克隆及其應(yīng)用。
6、2012.01-2014.12,教育部科學(xué)技術(shù)研究重點項目,212202,稻瘟病抗性基因Pi36互作蛋白的分子鑒定與功能研究。
7、2010.01-2012.12,湖北省自然科學(xué)杰出青年人才基金項目,2009CDA125,稻瘟病廣譜抗性基因Pita-2的克隆及其應(yīng)用。
8、2007.01-2009.12,國家自然科學(xué)青年基金項目,30600400,稻瘟病抗性基因Pi36的結(jié)構(gòu)及其功能研究。
9、2007.01-2009.12,武漢市青年科技晨光計劃,稻瘟病新抗性基因Pi39的定位及克隆”,200750731302。
10、2005.10-2008.10,中南民族大學(xué)自然科學(xué)基金重點項目,YZZ05012,水稻紅蓮型細胞質(zhì)雄性不育相關(guān)基因HL-sp1的克隆及功能研究。
(三)科研成果及榮譽
2015,榮獲國家民委突出貢獻專家
2015,全國五一巾幗標(biāo)兵集體獎,全國總工會,排名第一
2014,湖北省高校教師黨支部書記“雙帶頭人”稱號,湖北省高校工作委員會
2013,高產(chǎn)優(yōu)質(zhì)抗稻瘟病雜交中稻品種駿優(yōu)522的選育與推廣,湖北省科技進步三等獎,湖北省人民政府,排名第五
2008,The in Silico map-based cloning of Pi36, a rice coiled-coil-nucleotide-binding site-leucine-rich repeat gene that confers race-specific resistance to the blast fungus,湖北省第十二屆自然科學(xué)優(yōu)秀學(xué)術(shù)論文二等獎,湖北省科技廳
(四)代表性論文
1. Yanping Tan, Shiqi Deng, Yonghua Qin, Xin Xu, You Yu, Liu Cui, Chuntai Wang, Changjie Jiang*,Xinqiong Liu*. Evaluation of Medicinal Plant Extracts for the Control of Rice Blast Disease.Rice Science, 2023, 30(1): 6-10.
2.Yanping Tan,Xiaolin Yang,Minghao Pei,Xin Xu,Chuntai Wang,Xinqiong Liu*.A Genome-wide Survey of Interaction between Rice andMagnaporthe oryzaevia Microarray Analysis,Bioengineered,2021, 12(1):108-116
3.Xinqiong Liu#, HaruhikoInoue#, Xianying Tang,Yanping Tan, Xin Xu, Chuntai Wang, Changjie Jiang*. Rice OsAAA-ATPase1 is induced during blast infection in a salicylic acid-dependent manner, and promotes blast fungus resistance. Int. J. Mol. Sci. 2020, 21(4):1443-1459
4.YahongChen, Kang Dai, Hua Zhang, Yunhua. Wu, ChuntaiWang, XuequnLiu,XinqiongLiu*. Spectroscopic and molecular docking study on the interaction between salicylic acid and the induced disease-resistant protein OsAAA1 of rice. 2017, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 173, 1001–1006
5. Xinqiong Liu#, Haruhiko Inoue#, Nagao Hayashi, Chang-Jie Jiang,and Hiroshi Takatsuji*.CC-NBS-LRR-TypeR Proteins for Rice Blast Commonly Interact with Specific WRKY Transcription Factors, Plant Mol Biol Rep, 2015, 34: 533-537.
6.LixiaHua,L QLiang, HeX Y, WangL, ZhangW S,LiuW,XinqiongLiu,FeiLin. Development of a marker specific for the rice blast resistance gene Pi39 in the Chinese cultivar Q15 and its use in genetic improvement. Biotechnology & Biotechnological Equipment, 2015, 29(3), 448-456
7. DebingWang, YonghuaQin,JinluanHan, Zhang L,XinXu X, XinqiongLiu ,ChuntaiWangandXinqiongLiu*.Expression analysis of innate immunity related genes in the true/field blast resistance gene-mediated defence response. Biotechnology & Biotechnological Equipment, 2014, 28(6), 999-1007.
8. Han J L, Zhang X M, Zhang D, Liu X Q, Wang C T andXinqiongLiu*.Expression analysis ofOsbZIPtranscription factors in resistance response by the rice blast resistance genePi36-mediated. African Journal of Biotechnology, 2013, 12(34): 5294-5302
9. Jiang C J, Shimono M, Sugano S, Kojima M,XinqiongLiu, Inoue H, Sakakibara H, Takatsuji H*. Cytokinins act synergistically with salicylic acid to activate defense gene expression in rice, Mol Plant Microbe Interact, 26(3):287-296, 2013
10. Inoue H, Hayashi N, Matsushita A,XinqiongLiu, Nakayamab A, Sugano S, Jiang C J and Takatsuji H.Blast resistance of CC-NB-LRR protein Pb1 is mediated by WRKY45 through protein-protein interaction.Proc Natl Acad Sci USA, 2013, 110(23):9577–9582
11. He X Y#,XinqiongLiu#, Wang L,Lin F, Cheng Y S, Chen Z M, Liao Y P, Pan Q H. Identification of the novel recessive genepi55(t) conferring resistance toMagnaporthe oryzae. Sci China Life Sci, 2012, 55:141-9
12.XinqiongLiu, Zhang D, Zhang X M, Wang C T, Liu X Q, Tan Y P, Wu Y H. Study on the interaction between Methyl asmonate and the coiled-coil domain of rice blast resistance protein Pi36 by spectroscopic methods. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2012, 88:72–76
13.XinqiongLiuWei J L, Zhang J C, Wang C T, Liu X Q, Zhang X M, Wang L, Pan Q H. Genetic variation of rice blast resistance genes in oryza sativa and its wild relatives. Int J Plant Sci, 2011, 172(8):970–979
14. Chen S#,XinqiongLiu#, Zeng L X, Ouyang D M, Yang J Y, Zhu X Y. Genetic analysis and molecular mapping of a novel recessive genexa34(t) for resistance againstXanthomonas oryzae pv. Oryzae. Theor Appl Genet, 2011, 122:1331–1338
15.XinqiongLiu,Li Y, Wang L Y, Liu X, Wang C,Wang L,Pan Q H*. The effect of the rice blast resistance genePi36on the expression of disease resistance-related genes. Chinese Sci Bull,2010, 55: 1881-1888
16.XinqiongLiu,Wang L, Wang C, Liu X, Wang D, Lin F, Pan QH*. The molecular evolution of the rice blast resistance genePi36. Int J Plant Sci,2010, 171(3):235–243.
17.XinqiongLiu, Yang Q Z, Wang L, Hua L X, Lin F and Pan Q H*.Identification and fine mapping ofPi39(t), a major gene conferring the broad-spectrum resistance toMagnaporthe oryzae.Mol Genet Genomics, 2007, 278: 403–410
18.XinqiongLiu, Lin F,Wang L and Pan Q H*. Thein Silicomap-based cloning ofPi36, a rice coiled-coil–nucleotide-binding site–leucine-rich repeat gene that confers race-specific resistance to the blast fungus,Genetics, 2007,176: 2541–2549
19.Lin F,Chen S,Que Z,Wang L,XinqiongLiu,Pan Q*. The blast resistance genePi37encodes a nucleotide binding site leucine-rich repeat protein and is a member of a resistance gene cluster on rice chromosome 1. Genetics,2007, 177: 1871-80
20. Lin F, Liu Y G, Wang L,XinqiongLiu, Pan Q H*. A high-resolution map of the rice blast resistance genePi15was constructed by sequence-ready markers. Plant Breeding, 2007, 126: 287-290
21.XinqiongLiu, Wang L, Chen S, Lin F and Pan Q H*. Genetic and physical mapping ofPi36(t), a novel rice blast resistance gene located on rice chromosome 8. Mol Genet Genomics, 2005, 274: 394-401
22.陳佳瑩, 宋斯敏, 王春臺,劉新瓊*.稻瘟病新抗性基因Pi39候選基因Pi39E長片段載體的構(gòu)建.分子植物育種,2019,17( 9): 2882- 2885
23.張旺,陳佳瑩,王春臺,劉新瓊*.水稻誘導(dǎo)抗病基因OsAAA1啟動子構(gòu)建體的遺傳轉(zhuǎn)化與誘導(dǎo)表達.分子植物育種,2018,16(21):7021-7026
24.鄧霄霄,劉早利,王春臺,劉新瓊*,水稻OsAAA1基因啟動子的分離與克隆.分子植物育種, 2017,15(8): 827-831
25.劉早利,陳亞紅,王春臺,劉新瓊*.稻瘟病新抗性基因Pi39候選基因CRISPR/Cas9敲除載體的構(gòu)建.中國農(nóng)學(xué)通報, 2016, 32(6):91-95
26.田迪,劉早利,陳亞紅,王春臺,劉新瓊*.水稻細胞色素P450基因家族成員CYP81A6基因RNAi載體構(gòu)建.分子植物育種,2016, 14(2): 370-373
27.劉新瓊,徐瑋玉,劉早利,陳亞紅,程鋼.水稻OsAAA1蛋白的原核表達載體構(gòu)建及可溶性表達研究.中南民族大學(xué)學(xué)報(自然科學(xué)版). 2015, 34(2):18-22
28.袁坤,張丹,劉新瓊,張向明.實時熒光定量PCR反應(yīng)體系的優(yōu)化研究.廣東農(nóng)業(yè)科學(xué), 2013, 40(4):134-136
(五)發(fā)明專利
劉新瓊,張佑宏,楊小林,張向明,王春臺。一種七葉一枝花提取液的制備方法及其應(yīng)用,CN110663709B,授權(quán)日期2021.6,
劉新瓊,張佑宏,楊小林,張向明,王春臺。一種蓮子心提取液的制備方法及其應(yīng)用,CN110786341B,授權(quán)日期2021.4,
劉新瓊,徐鑫,譚艷平,王春臺,鄧霄霄。一種水稻誘導(dǎo)抗病基因OsAAA1啟動子及其載體與構(gòu)建方法,ZL201710341677,授權(quán)日期2019.11,
劉新瓊,姜昌杰,王春臺,程鋼,劉學(xué)群.一種水稻誘導(dǎo)抗病基因OsAAA1及其應(yīng)用,ZL201410591365.6,授權(quán)日期2016.8
潘慶華,王玲,林菲,劉新瓊.稻瘟病抗性基因Pi36及其應(yīng)用,ZL200610034048.X,2009
(六)著作
王春臺,劉新瓊,劉學(xué)群,等.圖解現(xiàn)代遺傳學(xué)實驗,化學(xué)工業(yè)出版社,2009,普通高等教育“十一五”規(guī)劃教材